Endocrine Abstracts

Background: Thyrotoxic crisis is a rare and life threatening condition requiring urgent medical intervention. Intrahepatic cholestasis, hypoglycaemia and pancytopenia are known but uncommon presentations in thyrotoxic crisis.Case presentation: A 71 year old Sri Lankan female with a background history of diabetes presented to a tertiary care centre with severe hypoglycaemic episodes despite being off oral hypoglycaemic agents, weight loss of 6 kg, palpita...

Introduction: Cushing’s syndrome usually presents with a phenotype including central obesity, striae, hypertension and diabetes. We report a case of Cushing’s syndrome presenting in an atypical manner.Case: A 73 year old lady was referred to neurology with a year’s history of progressive limb wasting, weakness and recurrent falls. The neurology team diagnosed accelerated sarcopenia. Investigations included CK (normal), EMG (suggested myopa...

Background: Diabetic neuropathy, especially distal symmetric polyneuropathy (DSPN), is a common but under-recognized problem among people living with diabetes, particularly in developing countries. Aims: We aimed to describe the clinical characteristics, associated factors, treatment practices, outcomes and impact of DSPN among Sri Lankan adults living with diabetes.Methods: A cross sectional study was conducted at the Diabetes Clinic of National Hospita...

Introduction: Hypoparathyroidism is most commonly observed following neck surgery and is characterized biochemically by deficient parathyroid hormone (PTH) and hypocalcaemia alongside hyperphosphataemia and reduced 1,25-dihydroxyvitamin D. Standard treatment with oral calcium and vitamin D aims to maintain serum calcium within the low-normal range whilst avoiding hypercalciuria due to over replacement. However, concerns remain over the presence of hypercalciuria and the associ...